Koichi S Kobayashi Selected Research

Interleukin-1 Receptor-Associated Kinases

5/2013	Altered gut microbiota promotes colitis-associated cancer in IL-1 receptor-associated kinase M-deficient mice.
9/2012	Interleukin-1 receptor-associated kinase M-deficient mice demonstrate an improved host defense during Gram-negative pneumonia.
6/2012	Interleukin 1 receptor-associated kinase m impairs host defense during pneumococcal pneumonia.
12/2011	Interleukin-1 receptor-associated kinase-M suppresses systemic lupus erythematosus.
10/2010	IL-1 receptor-associated kinase M downregulates DSS-induced colitis.

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Koichi S Kobayashi Research Topics

Disease

10	Infections 01/2013 - 11/2008
9	Neoplasms (Cancer) 01/2022 - 06/2009
4	Inflammation (Inflammations) 01/2018 - 08/2010
2	Colonic Neoplasms (Colon Cancer) 01/2022 - 05/2013
2	Pneumonia (Pneumonitis) 01/2015 - 09/2012
2	Septic Shock (Toxic Shock Syndrome) 11/2012 - 07/2009
2	Crohn Disease (Crohn's Disease) 04/2012 - 02/2005
2	Colitis 01/2011 - 10/2010
1	Melanoma (Melanoma, Malignant) 01/2021
1	Asthma (Bronchial Asthma) 01/2018
1	Mycoses (Diseases, Fungus) 05/2017
1	Bacterial Infections (Bacterial Infection) 01/2017
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 08/2015
1	Haemophilus Infections 01/2015
1	Atrophy 02/2014
1	Colitis-Associated Neoplasms 05/2013
1	Carcinogenesis 05/2013
1	Dysbiosis 04/2013
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 04/2013
1	Gram-Negative Bacterial Infections 11/2012
1	Pneumococcal Pneumonia 06/2012
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 12/2011
1	Escherichia coli Infections 11/2011
1	Chagas Disease (American Trypanosomiasis) 02/2010
1	Reperfusion Injury 07/2009
1	Ischemia 05/2008
1	Myocardial Infarction 05/2008
1	Anthrax 01/2008
1	Legionnaires' Disease (Legionnaire's Disease) 03/2006
1	Hyperthermia 03/2004
1	Dermatomyositis (Dermatopolymyositis) 08/2003
1	Muscle Weakness 08/2003
1	Myositis (Idiopathic Inflammatory Myopathies) 08/2003

Drug/Important Bio-Agent (IBA)

11	CytokinesIBA 01/2018 - 03/2004
7	Proteins (Proteins, Gene)FDA Link 01/2017 - 02/2005
6	Toll-Like Receptors (Toll-Like Receptor)IBA 08/2015 - 10/2010
5	Interleukin-1 Receptor-Associated KinasesIBA 05/2013 - 10/2010
4	NucleotidesIBA 01/2017 - 02/2010
3	Trans-Activators (Trans-Acting Factor)IBA 01/2021 - 05/2016
3	Phosphotransferases (Kinase)IBA 01/2018 - 05/2008
3	NLR ProteinsIBA 04/2013 - 11/2011
3	LipopolysaccharidesIBA 11/2012 - 07/2009
2	AntigensIBA 01/2021 - 08/2010
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 05/2016
1	Chimeric Antigen ReceptorsIBA 01/2022
1	Carcinoembryonic AntigenIBA 01/2022
1	Interleukin Receptors (Interleukin Receptor)IBA 01/2018
1	cis-trans-IsomerasesIBA 01/2018
1	Interleukin-33IBA 01/2018
1	Histocompatibility Antigens Class IIBA 05/2016
1	GlucocorticoidsIBA 01/2015
1	Etanercept (Enbrel)FDA Link 02/2014
1	DNA (Deoxyribonucleic Acid)IBA 02/2014
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 05/2013
1	Anti-Bacterial Agents (Antibiotics)IBA 05/2013
1	AzoxymethaneIBA 05/2013
1	CarcinogensIBA 05/2013
1	Dextrans (Dextran)FDA Link 05/2013
1	GlucuronidaseIBA 05/2013
1	Leucine (L-Leucine)FDA Link 04/2013
1	LigandsIBA 11/2012
1	Messenger RNA (mRNA)IBA 09/2012
1	ChemokinesIBA 09/2012
1	Cysteine Proteases (Cysteine Protease)IBA 01/2012
1	InflammasomesIBA 01/2012
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 11/2011
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2011
1	Interleukin-6 (Interleukin 6)IBA 11/2011
1	Chemokine CXCL2IBA 11/2011
1	Interleukin-23 (Interleukin 23)IBA 11/2011
1	Mitogen-Activated Protein KinasesIBA 11/2011
1	Interleukin-17 (Interleukin 17)IBA 11/2011
1	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 11/2011
1	Acetylmuramyl-Alanyl-IsoglutamineIBA 09/2011
1	Peptides (Polypeptides)IBA 09/2011
1	Dextran SulfateIBA 10/2010
1	Nitric Oxide Synthase (NO Synthase)IBA 02/2010
1	NF-kappa B (NF-kB)IBA 02/2010
1	CalciumIBA 06/2009
1	AerosolsIBA 11/2008
1	Type IV Secretion SystemsIBA 11/2008
1	p38 Mitogen-Activated Protein KinasesIBA 05/2008
1	Adenosine Triphosphate (ATP)IBA 05/2008
1	SB 203580IBA 05/2008
1	FlagellinIBA 01/2008
1	PyrinIBA 01/2008
1	Pattern Recognition ReceptorsIBA 03/2006
1	Creatine Kinase (Creatine Phosphokinase)IBA 08/2003
1	CollagenIBA 08/2003
1	Synaptotagmins (Synaptotagmin)IBA 08/2003
1	Antinuclear AntibodiesIBA 08/2003

Therapy/Procedure

5	Therapeutics 01/2022 - 10/2010
1	Immunotherapy 01/2021